Detalhe da pesquisa
1.
Novel Independent Trans- and Cis-Genetic Variants Associated with CYP2D6 Expression and Activity in Human Livers.
Drug Metab Dispos
; 52(2): 143-152, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38050015
2.
Identification of regulatory variants of carboxylesterase 1 (CES1): A proof-of-concept study for the application of the Allele-Specific Protein Expression (ASPE) assay in identifying cis-acting regulatory genetic polymorphisms.
Proteomics
; 23(1): e2200176, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36413357
3.
Genome-Wide Association Study for the Genetic Determinants of Thiopurine Methyltransferase Protein Expression in Human Livers and Racial Differences.
Pharm Res
; 40(11): 2525-2531, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37430149
4.
Transcriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice Isoforms.
Drug Metab Dispos
; 50(1): 43-48, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34697082
5.
Contributions of Cathepsin A and Carboxylesterase 1 to the Hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis.
Drug Metab Dispos
; 50(3): 243-248, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34933885
6.
Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes.
Drug Metab Dispos
; 50(4): 468-477, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34965924
7.
Effect of CES1 genetic variation on enalapril steady-state pharmacokinetics and pharmacodynamics in healthy subjects.
Br J Clin Pharmacol
; 87(12): 4691-4700, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33963573
8.
Data-independent acquisition (DIA): An emerging proteomics technology for analysis of drug-metabolizing enzymes and transporters.
Drug Discov Today Technol
; 39: 49-56, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34906325
9.
Genome-wide pQTL analysis of protein expression regulatory networks in the human liver.
BMC Biol
; 18(1): 97, 2020 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32778093
10.
FRACPRED-2D-PRM: A Fraction Prediction Algorithm-Assisted 2D Liquid Chromatography-Based Parallel Reaction Monitoring-Mass Spectrometry Approach for Measuring Low-Abundance Proteins in Human Plasma.
Proteomics
; 20(24): e2000175, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085175
11.
Carboxylesterase 1 and Precision Pharmacotherapy: Pharmacogenetics and Nongenetic Regulators.
Drug Metab Dispos
; 48(3): 230-244, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31871135
12.
Comparative Proteomics Analysis of Human Liver Microsomes and S9 Fractions.
Drug Metab Dispos
; 48(1): 31-40, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699809
13.
Acetaminophen-Induced Liver Injury Alters Expression and Activities of Cytochrome P450 Enzymes in an Age-Dependent Manner in Mouse Liver.
Drug Metab Dispos
; 48(5): 326-336, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32094214
14.
Chemoproteomic Identification of Serine Hydrolase RBBP9 as a Valacyclovir-Activating Enzyme.
Mol Pharm
; 17(5): 1706-1714, 2020 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32196348
15.
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)-Based Proteomics of Drug-Metabolizing Enzymes and Transporters.
Molecules
; 25(11)2020 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32545386
16.
Functional Study of Carboxylesterase 1 Protein Isoforms.
Proteomics
; 19(4): e1800288, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30520264
17.
Response to the Comments on "Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Proteomics Method".
J Proteome Res
; 18(3): 1458-1459, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30616350
18.
Potential Regulation of UGT2B10 and UGT2B7 by miR-485-5p in Human Liver.
Mol Pharmacol
; 96(6): 674-682, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31554697
19.
Identification of two novel epitopes targeting glycoprotein E of pseudorabies virus using monoclonal antibodies.
Biochem Biophys Res Commun
; 519(2): 330-336, 2019 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31514997
20.
Depolarization and repolarization parameters on ECG predict recurrence after atrial fibrillation ablation in patients with hypertrophic cardiomyopathy.
J Cardiovasc Electrophysiol
; 30(11): 2405-2413, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31441155